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The largest railroad terminal in the world opened its doors for the first time in 1913. And while Grand Central Terminal, in the heart of New York City, no longer serves long-distance trains, it is still a vibrant part of the city's ecosystem.

A voice from a bygone era, Lena Hughes was never very famous outside of her native Missouri. The only album she ever recorded has been saved from near-oblivion, and it acts as a kind of time capsule.

Arnold Schwarzenegger has lived a long life in just 65 years, from poor immigrant to giant bodybuilder, from Hollywood action star to governor of California. He recounts it all — his successes and failures, his dreams and challenges — in his new autobiography, Total Recall.

In 2003, a hospital nurse named Charlie Cullen was arrested under suspicion of injecting patients with lethal doses of a variety of medications. He is now considered one of the nation's most prolific serial killers. Journalist Charles Graeber explains how the hospital system failed to stop Cullen.

Journalist Jonathan Alter regards the 2012 presidential contest as the most consequential election of recent times. In his new book, Alter argues that President Obama's re-election prevented the country from veering sharply to the right, and he dissects the campaign and the events that led up to it.

Weekend Edition Saturday Host Scott Simon talks with bioethicist Arthur Caplan of New York University about Thursday's Supreme Court ruling that isolated human genes may not be patented — and the implications for that ruling.

As summer heads for fall: Serena Williams is poised to win again; football opens in earnest; and the real Olympic spirit is still on display. Host Scott Simon talks with NPR's Tom Goldman.

The Battle of Antietam was the bloodiest single day in American history, and the partial victory by Union troops led Abraham Lincoln to issue the Emancipation Proclamation. Monday marks the 150th anniversary of the Civil War battle that left 23,000 men killed or wounded on both sides.

Donald Trump has publicly attacked Megyn Kelly, a rising star at Fox News, for months. Mary Louise Kelly talks to Tucker Carlson of the Daily Caller and co-host of Fox & Friends Weekend for a preview.

The NBA playoffs start today and the Golden State Warriors are favored to win the title again this year, after finishing their regular season with the most wins ever.