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Drugs like Wegovy and Zepbound are highly effective for weight loss. But researchers at the Society for Neuroscience meeting say they are only beginning to understand the drugs' effects on the brain.

On Wild Card, well-known guests answer the kinds of questions we often think about but don't talk about. Malala Yousafzai talks about the advice from her parents she's glad she ignored.

Companies are testing autonomous big rigs on highways in Texas right now. The goal is to replace human truck drivers for at least some routes.

Four years after women with jobs were diagnosed with early-stage breast cancer, nearly one-third were unemployed. But it's not clear how much of that was due to illness or to a sour economy.

States have long sought to restrict cellphone use by drivers because of safety concerns, and as the new year begins, several states are toughening their laws. It turns out it's a hard habit to break. And for government officials, it's not easy to stay ahead of tech advances.

According to Gallup, Congress has never been more disliked in all the years it has been polling that question. Can it get any worse heading into the new year?

President Trump has been announcing new trade deals with foreign countries. But these frameworks are NOT binding — leaving businesses with lots of uncertainty.

NPR's Ailsa Chang speaks with Betsy Cooper, a cybersecurity expert at the Aspen Institute, about this week's major Internet outage and the world's reliance on a handful of web services companies.

More cracks emerged in the DOJ's prosecution against former FBI Director James Comey at a hearing WEdnesday.

The latest NPR, PBS News, Marist poll shows approval ratings tumbling for Republicans and low confidence in both major political parties.